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Case Studies

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Case Study 1: Silicosis

AGE
45
Sex
Male

INDICATIONS

  • Biopsy-proven silicosis
  • Ex-Smoker
  • Subjectively, right-sided chest discomfort with breathing
SUMMARY
  • Unable to complete spirometry
  • Strong pain on the right side
  • LVAS demonstrated a functional difference in ventilation on the right side
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Case Study 2: Non-Obstructive Atelectasis

AGE
69
Sex
Female

INDICATIONS

  • Past history of Covid-19
  • Gastric Oesophageal Reflux Disease
  • Recurrent chest infections
SUMMARY
  • Imaging showed a large hiatus hernia
  • LVAS demonstrated a greater functional reduction in ventilation than expected from CT changes
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Case Study 3: COPD With Biologic Therapy

AGE
60
Sex
Female

INDICATIONS

  • Prior biologics therapeutic for re-current exacerbation of moderate obstructive lung disease.
  • Medication: Fasenra (benralizumab)
SUMMARY
  • SOB for further investigation.
  • At baseline CT was unremarkable. Placed on biologics for history of exacerbation.
  • Following Tx, there are functional improvements in regional ventilation indices (reduced VH and VDP). Notably, appearance of improved ventilation, specifically in the dependent areas of the right and left lungs.
  • Corresponding with patient reported improvement in symptoms.
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Case Study 4: Long COVID-19 Symptoms

AGE
52
Sex
Female

INDICATIONS

  • Long COVID-19 symptoms.
SUMMARY
  • Patient hospitalised for COVID-19.
  • During hospital admission chest CT observed peripheral ground-glass and consolidative pulmonary opacities. (no XV LVAS imaging was captured)
  • Following Tx and discharge from hospital, the Pt continued to display symptoms of shortness of breath, cough and dyspnoea on exertion.
  • Following a physician consultation, the patient was referred for follow up CT and 4DMedical XV LVAS imaging.
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Clinical Observations

XV LVAS:
Follow up CT observed a resolution of the peripheral ground-glass and consolidative pulmonary opacities.
XV LVAS highlighted heterogeneity between the left and right lung regional performance.
Additionally, previous areas of ground-glass and consolidative pulmonary opacities displayed under ventilation specific to that region of the lung.
Chest CT: Acute COVID-19 Infection
Structural CT: Peripheral ground-glass and consolidative pulmonary opacities
3 Months Post-acute COVID-19 Infection
Structural CT
XV LVAS

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